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Dipak Mahajan
Dipak Mahajan

Gold Nanoparticles in Biosensing and Diagnostic Technologies

Biosensing technologies across the Americas increasingly rely on gold nanoparticles to enhance sensitivity, accuracy, and reliability. Their distinctive optical and electronic properties enable precise detection of biological signals, making them invaluable in diagnostic research and healthcare innovation.


Gold nanoparticles amplify signals in biosensors through surface plasmon resonance. When biological molecules bind to functionalized nanoparticles, measurable changes occur in optical or electrical properties. This amplification allows detection of biomarkers at extremely low concentrations, supporting early disease identification.


Customization is a key advantage. Researchers can functionalize gold nanoparticles with antibodies, enzymes, or nucleic acids that bind selectively to target molecules. This specificity minimizes false signals and improves diagnostic confidence. Such customization supports applications ranging from infectious disease detection to molecular diagnostics.


Point-of-care diagnostics benefit significantly from gold nanoparticle-based sensors. Compact and rapid testing platforms enable timely results outside traditional laboratory environments. This accessibility improves clinical decision-making and patient care delivery.


Gold nanoparticles also enhance multiplexed detection systems. By varying particle size or surface chemistry, researchers can design sensors capable of detecting multiple targets simultaneously. This capability increases efficiency and reduces diagnostic complexity.


Stability and durability further support biosensor performance. Gold nanoparticles resist degradation and maintain consistent behavior under diverse conditions. This reliability ensures reproducible results and long-term usability.


Safety and validation remain priorities. Diagnostic tools undergo rigorous testing to ensure accuracy and biocompatibility. Research teams continuously refine sensor designs to balance sensitivity with robustness.


Gold nanoparticles continue to advance biosensing technologies across the Americas, enabling precise, efficient, and reliable diagnostic solutions.



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